The fate of newly formed satellite cells during compensatory muscle hypertrophy.

نویسندگان

  • S Schiaffino
  • S P Bormioli
  • M Aloisi
چکیده

Compensatory hypertrophy was induced in the rat extensor digitorum longus muscle by extirpation of the synergistic tibialis anterior. Injections of 3H-thymidine (2 muCi/g body weight) was given at 24, 48, and 72 h after the operation. In animals killed immediately after the last injection both satellite cell nuclei and true muscle nuclei were labeled, whereas in animals killed 4 weeks later only true muscle nuclei were labeled. The results are interpreted as indicating incorporation of newly formed satellite cells into the fibers during compensatory hypertrophy.

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عنوان ژورنال:
  • Virchows Archiv. B, Cell pathology

دوره 21 2  شماره 

صفحات  -

تاریخ انتشار 1976